Tide Plus 10

Spironolactone is a synthetic steroid medication that functions as a competitive antagonist of aldosterone at the mineralocorticoid receptor, promoting sodium and water excretion while conserving potassium, thereby acting as a potassium-sparing diuretic.[1][2] It is primarily indicated for managing heart failure with reduced ejection fraction, essential hypertension, and edematous conditions stemming from hepatic cirrhosis or nephrotic syndrome, with additional applications in primary hyperaldosteronism and hypokalemia prevention during diuretic therapy.[1][3]