Rez-Q 300

Quinine is a naturally occurring cinchona alkaloid with the molecular formula C₂₀H₂₄N₂O₂, derived from the bark of trees in the genus Cinchona, native to the Andean forests of South America.[1][2] It functions primarily as an antimalarial agent by interfering with the parasite's heme detoxification process in Plasmodium species, particularly effective against severe falciparum malaria.[3] First utilized by indigenous Andean peoples for fevers and later adopted by Jesuits in the early 17th century, quinine extracts were introduced to Europe as "Jesuit's bark" and became the cornerstone of malaria treatment for centuries.[2] The pure compound was isolated in 1820 by French chemists Pierre Joseph Pelletier and Joseph Bienaimé Caventou, enabling standardized dosing and widespread pharmaceutical application.[3][1]