Ozotel-H

Hydrochlorothiazide is a thiazide-type diuretic medication that inhibits the sodium-chloride symporter in the distal convoluted tubule of the kidney, thereby increasing the excretion of sodium, chloride, and water to reduce fluid volume and lower blood pressure.[1] It is primarily used to treat hypertension and edema associated with conditions such as heart failure, liver cirrhosis, renal dysfunction, or corticosteroid/estrogen therapy.[2] Approved by the FDA, it is available in oral tablet and capsule forms, with a recommended starting dose of 25 mg once daily for hypertension in adults, preferably taken in the morning to minimize nocturia (nighttime urination) and sleep disruption caused by its diuretic effect; typical dosing ranges from 12.5 to 50 mg daily for hypertension and up to 200 mg for edema management.[1][3]