Migranil EC

Caffeine citrate is the citrate salt of caffeine, a naturally occurring methylxanthine alkaloid with the chemical formula C14H18N4O9 and a molecular weight of 386.31 g/mol.[1] It is formulated as a clear, colorless, sterile solution for intravenous injection or oral administration, containing 20 mg/mL of caffeine citrate (equivalent to 10 mg/mL of caffeine base), and is primarily indicated for the short-term treatment of apnea of prematurity in infants between 28 and less than 33 weeks gestational age, and is used off-label in more premature infants under 28 weeks gestational age.[2][3] As a central nervous system stimulant, caffeine citrate exerts its therapeutic effects through antagonism of adenosine receptors, thereby enhancing respiratory drive, improving diaphragmatic contractility, and reducing the frequency and severity of apneic episodes in preterm neonates.[2][4]